Recent newspaper articles highlight that Alzheimer’s cases in the U.S. are projected to double by 2050, and a recent blood test has been approved by the FDA to help diagnose the disease. Research also shows two phases of brain damage, one slow and silent and another rapid and destructive, along with studies on rare genetic mutations that may protect against the disease and a new model organism for studying Alzheimer’s.
Key Developments & Research
- Two Phases of Damage:
New research suggests Alzheimer’s may damage the brain in two distinct phases, with the first being slow and silent and the second involving more widespread, rapid destruction coinciding with symptoms.
- FDA-Approved Blood Test:
The Lumipulse G Plasma Ratio Test has been approved by the FDA to help diagnose Alzheimer’s by detecting plaque proteins in the blood, offering a new diagnostic tool for patients with cognitive decline.
- Genetic Insights:
Researchers are studying rare genetic mutations that can protect against Alzheimer’s, such as one linked to the APOE4 gene variant, which sheds light on potential ways to counter high-risk genes.
- New Research Model:
The common degu, a long-lived rodent, is emerging as a promising model for studying Alzheimer’s-like changes and aging-related neurodegeneration due to its natural development of relevant brain pathologies.
Future & Impact
- Increased Cases:
Due to an aging population, new cases of Alzheimer’s are expected to double by 2050, making research and early detection increasingly vital.
- Shift in Treatment:
The field is moving toward a more proactive approach, similar to managing heart disease, with a focus on early intervention, lifestyle changes, and combination therapies to target different aspects of the disease.
- Inspiring Future Scientists:
The increasing momentum in Alzheimer’s research is inspiring young physicians and scientists to join the field, bringing new energy to a previously challenging and uncertain area of medicine.
- Alzheimer’s Disease news – Today’s latest updates
Can Alzheimer’s be slowed? More than 7 million Americans live with Alzheimer’s. Aug 5. 04:40. FDA greenlights Alzheimer’s blood te…
CBS News

- Alzheimer’s disease – Latest research and news – Nature
The study of aging and age-related diseases has traditionally focused on short-lived laboratory species such as mice. The common d…
Nature

- Alzheimer’s disease may damage the brain in two phases
Oct 15, 2024 — Alzheimer’s disease may damage the brain in two distinct phases, based on new research funded by the National Institut…
National Institutes of Health (NIH) |

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